Nickel allergy to the percutaneous patent foramen ovale occluder and subsequent systemic nickel allergy

Systemic nickel allergy syndrome

Methods Demonstrate SNAS which is characterized by contact dermatitis to nickel and systemic reactions after ingestion of rich foods nickel.We evaluated adult patients with ages between 18 and 65 years, positive patch test for nickel, grades 3 and 4, and who had symptoms suggestive of SNAS.These patients had eczematous lesions of contact dermatitis did not disappear. That even with the exclusio...

GORE® Septal Occluder and Nickel Allergy

Nickel oral hyposensitization in patients with systemic nickel allergy syndrome

BACKGROUND This is the first randomized, double-blind, placebo-controlled trial (EUDRACT No. 2009-013923-43) evaluating nickel oral hyposensitizing treatment (NiOHT) in patients with "systemic nickel allergy syndrome" (SNAS), characterized by Ni-allergic contact dermatitis and systemic reactions after eating Ni-rich food. METHODS Adults with positive Ni-patch test, who reported symptoms sugge...

Reply to: Update on systemic nickel allergy syndrome and diet.

I am glad to reply to Goldenberg and Jacob’s observations, whom I thank for the kind attention given to my article. As a preliminary consideration, I wish to reiterate that my paper discussed exclusively the exposure to nickel via food; it didn’t discuss the other routes of systemic exposure. It distinguished allergic contact dermatitis (ACD) from systemic nickel allergy syndrome (SNAS) and, wi...

Granulomatous mass adherent to a patent foramen ovale occluder.

Kronmal RA. N-terminal pro-B-type natriuretic peptide is a major predictor of the development of atrial fibrillation: the Cardiovascular Health Study. Circulation 2009;120:1768–1774. 25. Wang TJ, Larson MG, Levy D, Benjamin EJ, Leip EP, Omland T, Wolf PA, Vasan RS. Plasma natriuretic peptide levels and the risk of cardiovascular events and death. N Engl J Med 2004;350:655–663. 26. Smith JG, New...